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Creators/Authors contains: "Glass, Michael"

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  1. This paper reports on two semesters experience with computer-mediated group discussion exercises in a CS2 computer programming class. The class is a gateway for computer science and computer engineering students, where many students have difficulty succeeding well enough to proceed in their major. The exercises focus on Java concepts. They are designed to require students to rely on each other, but also be individually accountable. Learning gains measured in this trial have been mixed, with the least prepared student (as measured by pretest) in each discussion group showing the highest learning gains, while best prepared student in the discussion group showed score reductions on average. This paper reports on first year results of learning gains and of surveys of student experience with the exercises 
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  2. COMPS computer-mediated group discussion exercises are being added to a second-semester computer programming class. The class is a gateway for computer science and computer engineering students, where many students have difficulty succeeding well enough to proceed in their major. This paper reports on first results of surveys on student experience with the exercises. It also reports on the affective states observed in the discussions that are candidates for analysis of group functioning. As a step toward computer monitoring of the discussions, an experiment in using dialogue features to identify the gender of the participants is described. 
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  3. Brain age (BA), distinct from chronological age (CA), can be estimated from MRIs to evaluate neuroanatomic aging in cognitively normal (CN) individuals. BA, however, is a cross-sectional measure that summarizes cumulative neuroanatomic aging since birth. Thus, it conveys poorly recent or contemporaneous aging trends, which can be better quantified by the (temporal) pace P of brain aging. Many approaches to map P, however, rely on quantifying DNA methylation in whole-blood cells, which the blood–brain barrier separates from neural brain cells. We introduce a three-dimensional convolutional neural network (3D-CNN) to estimate P noninvasively from longitudinal MRI. Our longitudinal model (LM) is trained on MRIs from 2,055 CN adults, validated in 1,304 CN adults, and further applied to an independent cohort of 104 CN adults and 140 patients with Alzheimer’s disease (AD). In its test set, the LM computes P with a mean absolute error (MAE) of 0.16 y (7% mean error). This significantly outperforms the most accurate cross-sectional model, whose MAE of 1.85 y has 83% error. By synergizing the LM with an interpretable CNN saliency approach, we map anatomic variations in regional brain aging rates that differ according to sex, decade of life, and neurocognitive status. LM estimates of P are significantly associated with changes in cognitive functioning across domains. This underscores the LM’s ability to estimate P in a way that captures the relationship between neuroanatomic and neurocognitive aging. This research complements existing strategies for AD risk assessment that estimate individuals’ rates of adverse cognitive change with age. 
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    Free, publicly-accessible full text available March 11, 2026